BA.5, immune escape

Vaccines and previous infections are protective against severe disease

Percentages of positives that were infected more than 90 days ago

Progressively increasing

Now, 12 % reinfections

3 months ago, 8% reinfections

6 months ago, 5% reinfections

https://www.youtube.com/watch?v=TwQp3Yc82ak

R = 1.1

Up 27% on the week

UK, 1 in 21

Scotland 1 in 15, highest ever rates

Young people and young adults highest

Will go up for a time, summer mixing, festivals

Consistent with ONS data

https://www.ons.gov.uk/peoplep....opulationandcommunit

One week ahead

Hospital admissions up 37%

List of covid symptoms

Runny nose, 66%

Sore throat, 65%

Headache, 64%

Persistent cough, 63%

Fatigue, 62%

Sneezing, 53%

Hoarse, 44%

Joint pains, 35%

Fever, 31%

Chills or shivers, 30%

Muscle pains 29%

Dizzy, 27%

Brain fog, 24%

Sore eyes, 22%

Altered smell, 21%

Lower back pain, 22%

Swollen glands, 19%

Skipped meals, 17%

Chest pain, 15%

BA.5 is milder than previous variants

Still time off work

Hospital admissions due to large numbers

Official data UK

https://coronavirus.data.gov.uk

Coronavirus vaccines should be updated for fall

https://www.fda.gov/advisory-c....ommittees/advisory-c

FDA advisory committee


Deadline, vaccine formula for October, now

BA.1 vaccine, in human tests for months

Arnold Monto, FDA advisory committee

We’re being asked, more or less, to have a crystal ball today

New multi-strain vaccine, original and omicron

Some wanted BA.4 and BA.5, others BA.1

Moderna, Novavax, Pfizer, each presented data to support their strategy

Moderna, bivalent, for example, original version + BA.1 variant

Pfizer BioNTech, only BA.1

Pfizer presented mouse data on BA.4 and BA.5

Novavax’s vaccine (not yet authorized in United States), additional doses of its existing vaccine could be protective

? will these new formulations apply to children without testing

? local or global

Lyme disease