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COVID-19 Vaccine Recommendations for Children and Teens

https://www.cdc.gov/coronaviru....s/2019-ncov/vaccines

What You Need to Know

CDC recommends everyone ages 5 years and older get vaccinated against COVID-19.

Everyone ages 5 years and older should also get a COVID-19 booster, when eligible.

Booster, at least 5 months after primary course

The Joint Committee on Vaccination and Immunisation (JCVI)

advise that all children aged 5 to 11 are offered the coronavirus (COVID-19) vaccine.

https://www.nhs.uk/conditions/....coronavirus-covid-19

https://www.nhsinform.scot/cov....id-19-vaccine/the-va

https://www.gov.uk/government/....publications/jcvi-up

UK, 5 million age 5 to 11

Children aged 5 to 11 years will be offered 2 doses of the coronavirus vaccine.

JCVI advises a non-urgent offer of two 10 mcg doses of the Pfizer-BioNTech COVID-19 vaccine (Comirnaty®) to children aged 5 to 11 years of age who are not in a clinical risk group.

What about natural immunity

Seroprevalence of Infection-Induced SARS-CoV-2 Antibodies — United States, September 2021–February 2022

https://www.cdc.gov/mmwr/volumes/71/wr/mm7117e3.htm?s_cid=mm7117e3_e&ACSTrackingID=USCDC_921-DM80513&ACSTrackingLabel=MMWR%20Early%20Release%20-%20Vol.%2071%2C%20April%2026%2C%202022&deliveryName=USCDC_921-DM80513

anti-N antibodies

As of February 2022, approximately 75% of children and adolescents had serologic evidence of previous infection with SARS-CoV-2, with approximately one third becoming newly seropositive since December 2021.

These findings illustrate a high infection rate for the Omicron variant, especially among children

https://www.pfizer.com/news/pr....ess-release/press-re

UK, percentage of the population estimated to have antibodies was high for children in Great Britain

https://www.ons.gov.uk/peoplep....opulationandcommunit

Antibodies against SARS-CoV-2 at or above 179 nanograms per millilitre (ng/ml), UK, 29 November 2021 to 15 May 2022

Testing negative means that an individual did not have enough antibodies to be detected in the test, not that they do not have any immune protection against the virus.

Pfizer booster dose, the evidence

https://www.pfizer.com/news/pr....ess-release/press-re

Thursday, April 14, 2022

Data from a subanalysis of 30 sera

clinical trial of children 5 through 11 years

36-fold increase in SARS-CoV-2 Omicron neutralizing titers following a booster (third) dose

Phase 2/3 clinical trial with 140 children

a booster (third) dose increased neutralizing antibodies by 6-fold against the SARS-CoV-2 wild-type strain

Cost of Pfizer vaccine for 5 to 11 year olds

https://www.pharmaceutical-tec....hnology.com/analysis

EU, $23.15 per dose

US, $24

UK, x 5,000,000 = $115,750,000

Per primary course, = $231,500,000

With third dose, $347,250,000

£289,000,000

US, x 24,000,000 = $576,000,000

Per primary course, $1,152,000,000

With third dose, $1,728,000,000

Why America Doesn't Trust the CDC

https://www.newsweek.com/why-a....merica-doesnt-trust-

MARTY MAKARY , PROFESSOR, JOHNS HOPKINS SCHOOL OF MEDICINE

Centers for Disease Control (CDC) vigorously recommended the booster for all 5 - 11

Pfizer spokesperson, it did not determine the efficacy of the booster in the 5-to-11-year-olds.

Advisory Committee on Immunization Practices (ACIP).

Eleven to one

Dr. Keipp Talbot, Vanderbilt University

vaccines, are not without their potential side effects

? sustainability of vaccinating the population every six months

Natural immunity

https://www.cdc.gov/mmwr/volum....es/71/wr/mm7104e1.ht

CDC data from New York and California demonstrated that natural immunity was 2.8 times more effective in preventing hospitalization

3.3 to 4.7 times more effective in preventing COVID infection compared to vaccination during the Delta wave.